Interaction effects: When features work together

Mon Jun 23 2025

You know that frustrating moment when your model performs beautifully in isolation, but falls apart when you add that one extra feature? That's often interaction effects at work - the hidden relationships between variables that can make or break your predictions.

If you've ever wondered why your house price model thinks a mansion in the middle of nowhere should cost the same as one in downtown San Francisco, you're already familiar with the problem. Let's dig into how these sneaky effects work and, more importantly, how to catch them before they mess up your results.

Understanding interaction effects

happen when features gang up on you. Instead of playing nice and adding their effects together, they start influencing each other in ways that can dramatically change your outcomes. Take that house pricing example - size matters, location matters, but size in that location matters in a completely different way.

Picture this: you're building a model to predict house prices. You've got square footage as one feature and neighborhood desirability as another. Simple enough, right? But here's where it gets interesting. A 3,000 square foot house in rural Kansas and the same house in Manhattan aren't just different by the sum of their parts - the interaction between size and location creates a whole new dynamic.

That's what makes interaction effects so tricky. They break the assumption that you can just add up individual feature contributions to get your final prediction. And trust me, they're everywhere in real-world data.

is one way to measure how strong these interactions are. It basically tells you what percentage of your model's behavior comes from features working together versus working alone. Yeah, it's computationally expensive (you'll be waiting a while on large datasets), but you can use sampling to speed things up if you don't mind a bit more uncertainty in your estimates.

The good news? Once you know interactions exist, you can use them to your advantage. are particularly good at capturing these effects automatically through their splitting process - they'll naturally create different branches for "large houses in good neighborhoods" versus "large houses in bad neighborhoods."

Detecting and measuring interaction effects

So how do you actually catch these interaction effects in the wild? You've got a few tools in your toolkit, and each tells you something different about what's going on.

Friedman's H-statistic is your quantitative friend here. As Christoph Molnar explains in his interpretable ML book, it gives you a number between 0 and 1 that represents how much of your model's variation comes from interactions. Zero means no interactions, one means it's all interactions all the time. Most real-world scenarios fall somewhere in between.

Regression analysis offers another angle - you can explicitly add interaction terms to your model and test if they're statistically significant. Jim Frost's guide shows how this works: multiply your features together and see if that new term improves your predictions. It's straightforward but can get messy fast if you have lots of features.

But numbers only tell part of the story. Visualization is where things really click. Here's what works:

  • Partial dependence plots: Show how your prediction changes as you vary one feature, averaged across all other features

  • ICE plots: Like partial dependence but for individual observations - great for spotting where interactions are strongest

  • 2D interaction plots: The classic approach - vary two features and use color or contours to show the prediction

This Medium post on feature interactions has some great visual examples if you want to see these in action. The key insight? If your partial dependence plots show different patterns for different subgroups, you've got interactions.

The team at Let's Data Science makes a good point: don't just detect interactions - understand them. Are they synergistic (features amplify each other) or antagonistic (features cancel out)? This understanding helps you decide whether to explicitly model the interaction or find a different approach entirely.

Interaction effects in A/B testing and experimentation

Here's where things get really interesting - and potentially messy. When you're running multiple experiments at once (and let's be honest, who isn't?), those experiments can start messing with each other's results.

Imagine you're testing a new checkout flow while your colleague is testing promotional banners. Seems harmless enough, right? But what if the banner promises "Quick checkout!" while your new flow actually adds an extra step for security? Suddenly, you're not just testing features - you're testing contradictions.

The good news is that Microsoft's experimentation platform team found that truly destructive interactions are pretty rare. Most of the time, your results stay directionally correct even if the exact numbers get a bit skewed. The interactions that really cause problems are usually obvious - like when two features literally fight for the same screen space.

Still, you need to check. Regression analysis can help here too. The basic approach:

  1. Tag users by which experiments they're in

  2. Add interaction terms to your analysis

  3. Check if being in both experiments creates effects beyond the sum of being in each one

If you do find significant interactions, you've got options:

  • Rerun with exclusive audiences: The nuclear option, but it works. Statsig's blog details how to split your traffic so experiments don't overlap.

  • Pick a winner manually: Sometimes you just need to make a call based on business priorities

  • Embrace the combo: If the interaction is actually positive, maybe you should ship both features together

  • Iterate on compatibility: Often a small tweak can eliminate the conflict

Tools like Statsig's Interaction Detection automate a lot of this heavy lifting. You pick two experiments, and it tells you if users exposed to both behave differently than expected. Simple, but it can save you from shipping features that work great alone but terrible together.

Managing interaction effects in practice

Alright, you've detected interaction effects. Now what? The temptation is to throw every possible interaction term into your model and call it a day. Please don't do that - you'll overfit faster than you can say "cross-validation."

The key is being selective about which interactions you include. Start with the ones that make intuitive sense or show up strongly in your H-statistic analysis. The interpretable ML book suggests focusing on interactions that either have strong theoretical backing or consistently show up across different datasets.

For visualization, you've got some solid options:

  • Partial dependence plots (PDPs): Great for overall trends

  • ICE plots: Perfect for spotting where specific observations behave differently

  • 2D heatmaps: Ideal when you need to show how two features interact

The folks at Medium's data science community have shown how combining these visualizations gives you both the forest and the trees view of your interactions.

When you're feeling adventurous, tools like genetic algorithms or symbolic regression can discover complex interactions you'd never think to test. Just remember - with great power comes great responsibility to validate your findings.

In the experimentation world, Statsig's Interaction Detection feature becomes your safety net. It's constantly checking if your concurrent experiments are playing nice together. When they're not, you get an early warning before bad data leads to bad decisions.

The workflow typically looks like this:

  1. Run your experiments normally

  2. Use statistical tests to check for interactions

  3. If found, decide whether to isolate experiments or embrace the interaction

  4. Document everything so the next person doesn't repeat your mistakes

Remember, not all interactions are bad. Sometimes features work better together than alone - that's a win worth exploring further. The goal isn't to eliminate all interactions, it's to understand and manage them.

Closing thoughts

Interaction effects are like that friend who seems quiet until you put them in the right group - suddenly they're changing the entire dynamic. They're not good or bad, they're just real, and ignoring them is like trying to predict the weather without considering how temperature and humidity work together.

The tools and techniques we've covered - from H-statistics to visualization methods to experimentation platforms - give you what you need to spot and handle these effects. Start simple with the interactions that make intuitive sense, then gradually expand your analysis as you get comfortable with the concepts.

Want to dive deeper? Check out:

Hope you find this useful! Now go forth and catch those sneaky interaction effects before they catch you.



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